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Knoblach, Susan

TitleAssistant Research Professor
InstitutionChildrens National Medical Center
DepartmentCenter for Genetic Medicine
Address111 Michigan Ave NW
Washington DC 20010
PhoneNA
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Muralidharan J, Ramezani A, Hubal M, Knoblach S, Shrivastav S, Karandish S, Scott R, Maxwell N, Ozturk S, Beddhu S, Kopp JB, Raj DS. Extracellular microRNA signature in chronic kidney disease. Am J Physiol Renal Physiol. 2017 Jun 01; 312(6):F982-F991. PMID: 28077372.
      View in: PubMed
    2. Orrock JE, Panchapakesan K, Vezina G, Chang T, Harris K, Wang Y, Knoblach S, Massaro AN. Association of brain injury and neonatal cytokine response during therapeutic hypothermia in newborns with hypoxic-ischemic encephalopathy. Pediatr Res. 2016 May; 79(5):742-7. PMID: 26717001; PMCID: PMC4853239.
    3. Hibino N, Best CA, Engle A, Ghimbovschi S, Knoblach S, Nath DS, Ishibashi N, Jonas RA. Novel Association of miR-451 with the Incidence of TEVG Stenosis in a Murine Model. Tissue Eng Part A. 2016 Jan; 22(1-2):75-82. PMID: 26573748; PMCID: PMC4741205 [Available on 01/01/17].
    4. Sokolowski K, Esumi S, Hirata T, Kamal Y, Tran T, Lam A, Oboti L, Brighthaupt SC, Zaghlula M, Martinez J, Ghimbovschi S, Knoblach S, Pierani A, Tamamaki N, Shah NM, Jones KS, Corbin JG. Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1. Neuron. 2015 Apr 22; 86(2):403-16. PMID: 25864637; PMCID: PMC4484744.
    5. Ramezani A, Devaney JM, Cohen S, Wing MR, Scott R, Knoblach S, Singhal R, Howard L, Kopp JB, Raj DS. Circulating and urinary microRNA profile in focal segmental glomerulosclerosis: a pilot study. Eur J Clin Invest. 2015 Apr; 45(4):394-404. PMID: 25682967; PMCID: PMC4903079.
    6. Dillingham BC, Knoblach SM, Many GM, Harmon BT, Mullen AM, Heier CR, Bello L, McCall JM, Hoffman EP, Connor EM, Nagaraju K, Reeves EKM, Damsker JM. VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis. Cell Mol Neurobiol. 2015 Apr; 35(3):377-387. PMID: 25392236.
      View in: PubMed
    7. Nalbandian A, Ghimbovschi S, Wang Z, Knoblach S, Llewellyn KJ, Vesa J, Hoffman EP, Kimonis VE. Global gene expression profiling in R155H knock-in murine model of VCP disease. Clin Transl Sci. 2015 Feb; 8(1):8-16. PMID: 25388089; PMCID: PMC4329058.
    8. Harness ET, Astorino TA, Knoblach SM, Feather J. Change in neuroplasticity-related proteins in response to acute activity-based therapy in persons with spinal cord injury. Top Spinal Cord Inj Rehabil. 2014; 20(2):147-57. PMID: 25477737; PMCID: PMC4252174.
    9. Yazdi PG, Su H, Ghimbovschi S, Fan W, Coskun PE, Nalbandian A, Knoblach S, Resnick JL, Hoffman E, Wallace DC, Kimonis VE. Differential gene expression reveals mitochondrial dysfunction in an imprinting center deletion mouse model of Prader-Willi syndrome. Clin Transl Sci. 2013 Oct; 6(5):347-55. PMID: 24127921; PMCID: PMC3815468.
    10. Fouts DE, Pieper R, Szpakowski S, Pohl H, Knoblach S, Suh MJ, Huang ST, Ljungberg I, Sprague BM, Lucas SK, Torralba M, Nelson KE, Groah SL. Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J Transl Med. 2012 Aug 28; 10:174. PMID: 22929533; PMCID: PMC3511201.
    11. Pajoohesh-Ganji A, Knoblach SM, Faden AI, Byrnes KR. Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. Brain Res. 2012 Sep 26; 1475:96-105. PMID: 22884909; PMCID: PMC3433585.
    12. Lerman BJ, Hoffman EP, Sutherland ML, Bouri K, Hsu DK, Liu FT, Rothstein JD, Knoblach SM. Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Brain Behav. 2012 Sep; 2(5):563-75. PMID: 23139902; PMCID: PMC3489809.
    13. Nalbandian A, Ghimbovschi S, Radom-Aizik S, Dec E, Vesa J, Martin B, Knoblach S, Smith C, Hoffman E, Kimonis VE. Global gene profiling of VCP-associated inclusion body myopathy. Clin Transl Sci. 2012 Jun; 5(3):226-34. PMID: 22686199; PMCID: PMC3375869.
    14. Byrnes KR, Washington PM, Knoblach SM, Hoffman E, Faden AI. Delayed inflammatory mRNA and protein expression after spinal cord injury. J Neuroinflammation. 2011 Oct 05; 8:130. PMID: 21975064; PMCID: PMC3198932.
    15. Chew LJ, Shen W, Ming X, Senatorov VV, Chen HL, Cheng Y, Hong E, Knoblach S, Gallo V. SRY-box containing gene 17 regulates the Wnt/ß-catenin signaling pathway in oligodendrocyte progenitor cells. J Neurosci. 2011 Sep 28; 31(39):13921-35. PMID: 21957254; PMCID: PMC3227525.
    16. Rayavarapu S, Van der Meulen JH, Gordish-Dressman H, Hoffman EP, Nagaraju K, Knoblach SM. Characterization of dysferlin deficient SJL/J mice to assess preclinical drug efficacy: fasudil exacerbates muscle disease phenotype. PLoS One. 2010 Sep 24; 5(9):e12981. PMID: 20886045; PMCID: PMC2945315.
    17. Kim B, Lee B, Knoblach S, Hoffman E, Seo J. GeneShelf: a web-based visual interface for large gene expression time-series data repositories. IEEE Trans Vis Comput Graph. 2009 Nov-Dec; 15(6):905-12. PMID: 19834153.
      View in: PubMed
    18. Kesari A, Fukuda M, Knoblach S, Bashir R, Nader GA, Rao D, Nagaraju K, Hoffman EP. Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset. Am J Pathol. 2008 Nov; 173(5):1476-87. PMID: 18832576; PMCID: PMC2570137.
    19. Spurney CF, Knoblach S, Pistilli EE, Nagaraju K, Martin GR, Hoffman EP. Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart. Neuromuscul Disord. 2008 May; 18(5):371-81. PMID: 18440230; PMCID: PMC2430663.
    20. Byrnes KR, Garay J, Di Giovanni S, De Biase A, Knoblach SM, Hoffman EP, Movsesyan V, Faden AI. Expression of two temporally distinct microglia-related gene clusters after spinal cord injury. Glia. 2006 Mar; 53(4):420-33. PMID: 16345062.
      View in: PubMed
    21. Faden AI, Movsesyan VA, Knoblach SM, Ahmed F, Cernak I. Neuroprotective effects of novel small peptides in vitro and after brain injury. Neuropharmacology. 2005 Sep; 49(3):410-24. PMID: 15907950.
      View in: PubMed
    22. Faden AI, Knoblach SM, Movsesyan VA, Lea PM, Cernak I. Novel neuroprotective tripeptides and dipeptides. Ann N Y Acad Sci. 2005 Aug; 1053:472-81. PMID: 16179555.
      View in: PubMed
    23. Stoica BA, Movsesyan VA, Knoblach SM, Faden AI. Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. Mol Cell Neurosci. 2005 Jul; 29(3):355-71. PMID: 15905098.
      View in: PubMed
    24. De Biase A, Knoblach SM, Di Giovanni S, Fan C, Molon A, Hoffman EP, Faden AI. Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. Physiol Genomics. 2005 Aug 11; 22(3):368-81. PMID: 15942019.
      View in: PubMed
    25. Knoblach SM, Huang X, VanGelderen J, Calva-Cerqueira D, Faden AI. Selective caspase activation may contribute to neurological dysfunction after experimental spinal cord trauma. J Neurosci Res. 2005 May 01; 80(3):369-80. PMID: 15795935.
      View in: PubMed
    26. Faden AI, Knoblach SM, Movsesyan VA, Cernak I. Novel small peptides with neuroprotective and nootropic properties. J Alzheimers Dis. 2004 Dec; 6(6 Suppl):S93-7. PMID: 15665420.
      View in: PubMed
    27. Di Giovanni S, Faden AI, Yakovlev A, Duke-Cohan JS, Finn T, Thouin M, Knoblach S, De Biase A, Bregman BS, Hoffman EP. Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth. FASEB J. 2005 Jan; 19(1):153-4. PMID: 15522907.
      View in: PubMed
    28. Knoblach SM, Alroy DA, Nikolaeva M, Cernak I, Stoica BA, Faden AI. Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury. J Cereb Blood Flow Metab. 2004 Oct; 24(10):1119-32. PMID: 15529012.
      View in: PubMed
    29. Movsesyan VA, Stoica BA, Yakovlev AG, Knoblach SM, Lea PM, Cernak I, Vink R, Faden AI. Anandamide-induced cell death in primary neuronal cultures: role of calpain and caspase pathways. Cell Death Differ. 2004 Oct; 11(10):1121-32. PMID: 15375383.
      View in: PubMed
    30. Cernak I, Vink R, Natale J, Stoica B, Lea PM, Movsesyan V, Ahmed F, Knoblach SM, Fricke ST, Faden AI. The "dark side" of endocannabinoids: a neurotoxic role for anandamide. J Cereb Blood Flow Metab. 2004 May; 24(5):564-78. PMID: 15129189.
      View in: PubMed
    31. Di Giovanni S, Knoblach SM, Brandoli C, Aden SA, Hoffman EP, Faden AI. Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Ann Neurol. 2003 Apr; 53(4):454-68. PMID: 12666113.
      View in: PubMed
    32. Faden AI, Knoblach SM, Cernak I, Fan L, Vink R, Araldi GL, Fricke ST, Roth BL, Kozikowski AP. Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo. J Cereb Blood Flow Metab. 2003 Mar; 23(3):342-54. PMID: 12621309.
      View in: PubMed
    33. Faden AI, Fox GB, Di X, Knoblach SM, Cernak I, Mullins P, Nikolaeva M, Kozikowski AP. Neuroprotective and nootropic actions of a novel cyclized dipeptide after controlled cortical impact injury in mice. J Cereb Blood Flow Metab. 2003 Mar; 23(3):355-63. PMID: 12621310.
      View in: PubMed
    34. Knoblach SM, Nikolaeva M, Huang X, Fan L, Krajewski S, Reed JC, Faden AI. Multiple caspases are activated after traumatic brain injury: evidence for involvement in functional outcome. J Neurotrauma. 2002 Oct; 19(10):1155-70. PMID: 12427325.
      View in: PubMed
    35. Prakash KR, Tang Y, Kozikowski AP, Flippen-Anderson JL, Knoblach SM, Faden AI. Synthesis and biological activity of novel neuroprotective diketopiperazines. Bioorg Med Chem. 2002 Sep; 10(9):3043-8. PMID: 12110327.
      View in: PubMed
    36. Knoblach SM, Faden AI. Administration of either anti-intercellular adhesion molecule-1 or a nonspecific control antibody improves recovery after traumatic brain injury in the rat. J Neurotrauma. 2002 Sep; 19(9):1039-50. PMID: 12482117.
      View in: PubMed
    37. Allen JW, Eldadah BA, Huang X, Knoblach SM, Faden AI. Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. J Neurosci Res. 2001 Jul 01; 65(1):45-53. PMID: 11433428.
      View in: PubMed
    38. Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 2001 Jan; 296(1):41-7. PMID: 11123360.
      View in: PubMed
    39. Knoblach SM, Faden AI. Cortical interleukin-1 beta elevation after traumatic brain injury in the rat: no effect of two selective antagonists on motor recovery. Neurosci Lett. 2000 Jul 28; 289(1):5-8. PMID: 10899395.
      View in: PubMed
    40. Allen JW, Knoblach SM, Faden AI. Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro. Cell Death Differ. 2000 May; 7(5):470-6. PMID: 10800080.
      View in: PubMed
    41. Albensi BC, Knoblach SM, Chew BG, O'Reilly MP, Faden AI, Pekar JJ. Diffusion and high resolution MRI of traumatic brain injury in rats: time course and correlation with histology. Exp Neurol. 2000 Mar; 162(1):61-72. PMID: 10716889.
      View in: PubMed
    42. Allen JW, Knoblach SM, Faden AI. Combined mechanical trauma and metabolic impairment in vitro induces NMDA receptor-dependent neuronal cell death and caspase-3-dependent apoptosis. FASEB J. 1999 Oct; 13(13):1875-82. PMID: 10506592.
      View in: PubMed
    43. Knoblach SM, Fan L, Faden AI. Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment. J Neuroimmunol. 1999 Mar 01; 95(1-2):115-25. PMID: 10229121.
      View in: PubMed
    44. Faden AI, Fox G, Fan L, Knoblach S, Araldi GL, Kozikowski AP. Neuroprotective and cognitive enhancing effects of novel small peptides. Ann N Y Acad Sci. 1999; 890:120. PMID: 10668419.
      View in: PubMed
    45. Knoblach SM, Faden AI. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol. 1998 Sep; 153(1):143-51. PMID: 9743576.
      View in: PubMed
    46. Yakovlev AG, Knoblach SM, Fan L, Fox GB, Goodnight R, Faden AI. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci. 1997 Oct 01; 17(19):7415-24. PMID: 9295387.
      View in: PubMed
    47. Mukhin AG, Ivanova SA, Knoblach SM, Faden AI. New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity. J Neurotrauma. 1997 Sep; 14(9):651-63. PMID: 9337127.
      View in: PubMed
    48. Knoblach SM, Kubek MJ. Increases in thyrotropin-releasing hormone messenger RNA expression induced by a model of human temporal lobe epilepsy: effect of partial and complete kindling. Neuroscience. 1997 Jan; 76(1):85-95. PMID: 8971761.
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    49. Knoblach SM, Kubek MJ. Changes in thyrotropin-releasing hormone levels in hippocampal subregions induced by a model of human temporal lobe epilepsy: effect of partial and complete kindling. Neuroscience. 1997 Jan; 76(1):97-104. PMID: 8971762.
      View in: PubMed
    50. Knoblach SM, Kubek MJ. Thyrotropin-releasing hormone release is enhanced in hippocampal slices after electroconvulsive shock. J Neurochem. 1994 Jan; 62(1):119-25. PMID: 8263511.
      View in: PubMed
    51. Kubek MJ, Knoblach SM, Sharif NA, Burt DR, Buterbaugh GG, Fuson KS. Thyrotropin-releasing hormone gene expression and receptors are differentially modified in limbic foci by seizures. Ann Neurol. 1993 Jan; 33(1):70-6. PMID: 8388190.
      View in: PubMed
    52. Vink R, Noble LJ, Knoblach SM, Bendall MR, Faden AI. Metabolic changes in rabbit spinal cord after trauma: magnetic resonance spectroscopy studies. Ann Neurol. 1989 Jan; 25(1):26-31. PMID: 2913925.
      View in: PubMed
    53. Vink R, Knoblach SM, Faden AI. 31P magnetic resonance spectroscopy of traumatic spinal cord injury. Magn Reson Med. 1987 Oct; 5(4):390-4. PMID: 3683171.
      View in: PubMed
    54. Faden AI, Knoblach S, Mays C, Jacobs TP. Motor dysfunction after spinal cord injury is mediated by opiate receptors. Peptides. 1985; 6 Suppl 1:15-7. PMID: 2995941.
      View in: PubMed
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