Header Logo

Please contact dabioye@childrensnational.org for any questions. Can't find your name in profiles ? Request a Profile

Last Name

Spurney, Chris

TitleAssociate Professor
InstitutionChildrens National Medical Center
Address111 Michigan Ave NW
Washington DC 20010
Phone(202) 4766231
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Spurney CF. Response to Letter to the Editor. Pediatr Cardiol. 2018 01; 39(1):204-205. PMID: 29247334.
      View in: PubMed
    2. Siegel B, Olivieri L, Gordish-Dressman H, Spurney CF. Myocardial Strain Using Cardiac MR Feature Tracking and Speckle Tracking Echocardiography in Duchenne Muscular Dystrophy Patients. Pediatr Cardiol. 2018 Mar; 39(3):478-483. PMID: 29188318.
      View in: PubMed
    3. Lopez L, Colan S, Stylianou M, Granger S, Trachtenberg F, Frommelt P, Pearson G, Camarda J, Cnota J, Cohen M, Dragulescu A, Frommelt M, Garuba O, Johnson T, Lai W, Mahgerefteh J, Pignatelli R, Prakash A, Sachdeva R, Soriano B, Soslow J, Spurney C, Srivastava S, Taylor C, Thankavel P, van der Velde M, Minich L. Relationship of Echocardiographic Z Scores Adjusted for Body Surface Area to Age, Sex, Race, and Ethnicity: The Pediatric Heart Network Normal Echocardiogram Database. Circ Cardiovasc Imaging. 2017 Nov; 10(11). PMID: 29138232.
      View in: PubMed
    4. Anderson J, Seol H, Gordish-Dressman H, Hathout Y, Spurney CF. Interleukin 1 Receptor-Like 1 Protein (ST2) is a Potential Biomarker for Cardiomyopathy in Duchenne Muscular Dystrophy. Pediatr Cardiol. 2017 Dec; 38(8):1606-1612. PMID: 28821969.
      View in: PubMed
    5. Olivieri LJ, Kellman P, McCarter RJ, Cross RR, Hansen MS, Spurney CF. Native T1 values identify myocardial changes and stratify disease severity in patients with Duchenne muscular dystrophy. J Cardiovasc Magn Reson. 2016 Oct 28; 18(1):72. PMID: 27788681.
      View in: PubMed
    6. Punnoose AR, Kaltman JR, Pastor W, McCarter R, He J, Spurney CF. Cardiac Disease Burden and Risk of Mortality in Hospitalized Muscular Dystrophy Patients. Pediatr Cardiol. 2016 Oct; 37(7):1290-6. PMID: 27314489.
      View in: PubMed
    7. Duan D, Rafael-Fortney JA, Blain A, Kass DA, McNally EM, Metzger JM, Spurney CF, Kinnett K. Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy. J Cardiovasc Transl Res. 2016 Feb; 9(1):85-6. PMID: 26718928.
      View in: PubMed
    8. Narayanaswami P, Dubinsky R, Wang D, Gjorvad G, David W, Finder J, Smith B, Cheng J, Shapiro F, Mellion M, Spurney C, Wolff J, England J. Quality improvement in neurology: muscular dystrophy quality measures. Neurology. 2015 Sep 08; 85(10):905-9. PMID: 26333798; PMCID: PMC4560061.
    9. Dillingham BC, Benny Klimek ME, Gernapudi R, Rayavarapu S, Gallardo E, Van der Meulen JH, Jordan S, Ampong B, Gordish-Dressman H, Spurney CF, Nagaraju K. Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice. J Neurol Sci. 2015 Sep 15; 356(1-2):157-62. PMID: 26119397; PMCID: PMC4545396.
    10. McNally EM, Kaltman JR, Benson DW, Canter CE, Cripe LH, Duan D, Finder JD, Groh WJ, Hoffman EP, Judge DP, Kertesz N, Kinnett K, Kirsch R, Metzger JM, Pearson GD, Rafael-Fortney JA, Raman SV, Spurney CF, Targum SL, Wagner KR, Markham LW. Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy. Circulation. 2015 May 05; 131(18):1590-8. PMID: 25940966; PMCID: PMC4573596.
    11. Spurney CF, McCaffrey FM, Cnaan A, Morgenroth LP, Ghelani SJ, Gordish-Dressman H, Arrieta A, Connolly AM, Lotze TE, McDonald CM, Leshner RT, Clemens PR. Feasibility and Reproducibility of Echocardiographic Measures in Children with Muscular Dystrophies. J Am Soc Echocardiogr. 2015 Aug; 28(8):999-1008. PMID: 25906753; PMCID: PMC4526320.
    12. Mak IT, Kramer JH, Chmielinska JJ, Spurney CF, Weglicki WB. EGFR-TKI, erlotinib, causes hypomagnesemia, oxidative stress, and cardiac dysfunction: attenuation by NK-1 receptor blockade. J Cardiovasc Pharmacol. 2015 Jan; 65(1):54-61. PMID: 25343568; PMCID: PMC4286425.
    13. Riley A, Sable C, Prasad A, Spurney C, Harahsheh A, Clauss S, Colyer J, Gierdalski M, Johnson A, Pearson GD, Rosenthal J. Utility of hand-held echocardiography in outpatient pediatric cardiology management. Pediatr Cardiol. 2014 Dec; 35(8):1379-86. PMID: 24913414.
      View in: PubMed
    14. Spurney C, Shimizu R, Morgenroth LP, Kolski H, Gordish-Dressman H, Clemens PR. Cooperative International Neuromuscular Research Group Duchenne Natural History Study demonstrates insufficient diagnosis and treatment of cardiomyopathy in Duchenne muscular dystrophy. Muscle Nerve. 2014 Aug; 50(2):250-6. PMID: 24395289; PMCID: PMC4081523.
    15. Kornegay JN, Spurney CF, Nghiem PP, Brinkmeyer-Langford CL, Hoffman EP, Nagaraju K. Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials. ILAR J. 2014; 55(1):119-49. PMID: 24936034; PMCID: PMC4158345.
    16. Mak IT, Kramer JH, Chen X, Chmielinska JJ, Spurney CF, Weglicki WB. Mg supplementation attenuates ritonavir-induced hyperlipidemia, oxidative stress, and cardiac dysfunction in rats. Am J Physiol Regul Integr Comp Physiol. 2013 Nov 15; 305(10):R1102-11. PMID: 24049113; PMCID: PMC3841797.
    17. Sali A, Many GM, Gordish-Dressman H, van der Meulen JH, Phadke A, Spurney CF, Cnaan A, Hoffman EP, Nagaraju K. The proton pump inhibitor lansoprazole improves the skeletal phenotype in dystrophin deficient mdx mice. PLoS One. 2013; 8(7):e66617. PMID: 23843959; PMCID: PMC3699610.
    18. Yu Q, Sali A, Van der Meulen J, Creeden BK, Gordish-Dressman H, Rutkowski A, Rayavarapu S, Uaesoontrachoon K, Huynh T, Nagaraju K, Spurney CF. Omigapil treatment decreases fibrosis and improves respiratory rate in dy(2J) mouse model of congenital muscular dystrophy. PLoS One. 2013; 8(6):e65468. PMID: 23762378; PMCID: PMC3675144.
    19. Ghelani SJ, Kwatra NS, Spurney CF. Can Coronary Artery Involvement in Kawasaki Disease be Predicted? Diagnostics (Basel). 2013 Mar 26; 3(2):232-43. PMID: 26835677; PMCID: PMC4665533.
    20. Ghelani SJ, Spurney CF, Martin GR, Cross RR. Impact of pharmacotherapy on interstage mortality and weight gain in children with single ventricle. Congenit Heart Dis. 2013 May-Jun; 8(3):219-27. PMID: 23157489.
      View in: PubMed
    21. Kramer JH, Spurney CF, Iantorno M, Tziros C, Chmielinska JJ, Mak IT, Weglicki WB. d-Propranolol protects against oxidative stress and progressive cardiac dysfunction in iron overloaded rats. Can J Physiol Pharmacol. 2012 Sep; 90(9):1257-68. PMID: 22913465; PMCID: PMC3715050.
    22. Ghelani SJ, Spaeder MC, Pastor W, Spurney CF, Klugman D. Demographics, trends, and outcomes in pediatric acute myocarditis in the United States, 2006 to 2011. Circ Cardiovasc Qual Outcomes. 2012 Sep 01; 5(5):622-7. PMID: 22828827.
      View in: PubMed
    23. Weglicki WB, Kramer JH, Spurney CF, Chmielinska JJ, Mak IT. The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction. Can J Physiol Pharmacol. 2012 Aug; 90(8):1145-9. PMID: 22646904; PMCID: PMC3734545.
    24. Sali A, Guerron AD, Gordish-Dressman H, Spurney CF, Iantorno M, Hoffman EP, Nagaraju K. Glucocorticoid-treated mice are an inappropriate positive control for long-term preclinical studies in the mdx mouse. PLoS One. 2012; 7(4):e34204. PMID: 22509280; PMCID: PMC3317932.
    25. Ghelani SJ, Sable C, Wiedermann BL, Spurney CF. Increased incidence of incomplete Kawasaki disease at a pediatric hospital after publication of the 2004 American Heart Association guidelines. Pediatr Cardiol. 2012 Oct; 33(7):1097-103. PMID: 22349679.
      View in: PubMed
    26. Spurney C, Yu Q, Nagaraju K. Speckle tracking analysis of the left ventricular anterior wall shows significantly decreased relative radial strain patterns in dystrophin deficient mice after 9 months of age. PLoS Curr. 2011 Oct 19; 3:RRN1273. PMID: 22307449; PMCID: PMC3269805.
    27. Spurney CF. Cardiomyopathy of Duchenne muscular dystrophy: current understanding and future directions. Muscle Nerve. 2011 Jul; 44(1):8-19. PMID: 21674516.
      View in: PubMed
    28. Spurney CF, Rocha CT, Henricson E, Florence J, Mayhew J, Gorni K, Pasquali L, Pestronk A, Martin GR, Hu F, Nie L, Connolly AM, Escolar DM. CINRG pilot trial of coenzyme Q10 in steroid-treated Duchenne muscular dystrophy. Muscle Nerve. 2011 Aug; 44(2):174-8. PMID: 21698649; PMCID: PMC3136634.
    29. Spurney CF, Guerron AD, Yu Q, Sali A, van der Meulen JH, Hoffman EP, Nagaraju K. Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice. BMC Cardiovasc Disord. 2011 May 16; 11:20. PMID: 21575230; PMCID: PMC3123649.
    30. Spurney CF, Sali A, Guerron AD, Iantorno M, Yu Q, Gordish-Dressman H, Rayavarapu S, van der Meulen J, Hoffman EP, Nagaraju K. Losartan decreases cardiac muscle fibrosis and improves cardiac function in dystrophin-deficient mdx mice. J Cardiovasc Pharmacol Ther. 2011 Mar; 16(1):87-95. PMID: 21304057; PMCID: PMC4147941.
    31. Mak IT, Chmielinska JJ, Kramer JH, Spurney CF, Weglicki WB. Loss of neutral endopeptidase activity contributes to neutrophil activation and cardiac dysfunction during chronic hypomagnesemia: Protection by substance P receptor blockade. Exp Clin Cardiol. 2011; 16(4):121-4. PMID: 22131854; PMCID: PMC3206104.
    32. Leckey LC, Garige M, Varatharajalu R, Gong M, Nagata T, Spurney CF, Lakshman RM. Quercetin and ethanol attenuate the progression of atherosclerotic plaques with concomitant up regulation of paraoxonase1 (PON1) gene expression and PON1 activity in LDLR-/- mice. Alcohol Clin Exp Res. 2010 Sep 01; 34(9):1535-42. PMID: 20586760; PMCID: PMC2929280.
    33. Guerron AD, Rawat R, Sali A, Spurney CF, Pistilli E, Cha HJ, Pandey GS, Gernapudi R, Francia D, Farajian V, Escolar DM, Bossi L, Becker M, Zerr P, de la Porte S, Gordish-Dressman H, Partridge T, Hoffman EP, Nagaraju K. Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy. PLoS One. 2010 Jun 21; 5(6):e11220. PMID: 20574530; PMCID: PMC2888587.
    34. Spurney CF, Cha HJ, Sali A, Pandey GS, Pistilli E, Guerron AD, Gordish-Dressman H, Hoffman EP, Nagaraju K. Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse. PLoS One. 2010 Jan 29; 5(1):e8976. PMID: 20126456; PMCID: PMC2813286.
    35. Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV. Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. J Clin Invest. 2009 Nov; 119(11):3420-36. PMID: 19855129.
      View in: PubMed
    36. Weglicki WB, Chmielinska JJ, Tejero-Taldo I, Kramer JH, Spurney CF, Viswalingham K, Lu B, Mak IT. Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemia. Magnes Res. 2009 Sep; 22(3):167S-173S. PMID: 19780404; PMCID: PMC3800095.
    37. Kesari A, Neel R, Wagoner L, Harmon B, Spurney C, Hoffman EP. Somatic mosaicism for Duchenne dystrophy: evidence for genetic normalization mitigating muscle symptoms. Am J Med Genet A. 2009 Jul; 149A(7):1499-503. PMID: 19530190; PMCID: PMC2729699.
    38. Kramer JH, Spurney C, Iantorno M, Tziros C, Mak IT, Tejero-Taldo MI, Chmielinska JJ, Komarov AM, Weglicki WB. Neurogenic inflammation and cardiac dysfunction due to hypomagnesemia. Am J Med Sci. 2009 Jul; 338(1):22-7. PMID: 19593099; PMCID: PMC3753099.
    39. Spurney CF, Gordish-Dressman H, Guerron AD, Sali A, Pandey GS, Rawat R, Van Der Meulen JH, Cha HJ, Pistilli EE, Partridge TA, Hoffman EP, Nagaraju K. Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures. Muscle Nerve. 2009 May; 39(5):591-602. PMID: 19260102.
      View in: PubMed
    40. Brown J, Nunez S, Russell M, Spurney C. Hypocalcemic rickets and dilated cardiomyopathy: case reports and review of literature. Pediatr Cardiol. 2009 Aug; 30(6):818-23. PMID: 19387720.
      View in: PubMed
    41. Wu B, Moulton HM, Iversen PL, Jiang J, Li J, Li J, Spurney CF, Sali A, Guerron AD, Nagaraju K, Doran T, Lu P, Xiao X, Lu QL. Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):14814-9. PMID: 18806224; PMCID: PMC2546441.
    42. Spurney CF, Knoblach S, Pistilli EE, Nagaraju K, Martin GR, Hoffman EP. Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart. Neuromuscul Disord. 2008 May; 18(5):371-81. PMID: 18440230; PMCID: PMC2430663.
    43. Spurney CF, Lo CW, Leatherbury L. Fetal mouse imaging using echocardiography: a review of current technology. Echocardiography. 2006 Nov; 23(10):891-9. PMID: 17069613.
      View in: PubMed
    44. Spurney CF, Sable CA, Berger JT, Martin GR. Use of a hand-carried ultrasound device by critical care physicians for the diagnosis of pericardial effusions, decreased cardiac function, and left ventricular enlargement in pediatric patients. J Am Soc Echocardiogr. 2005 Apr; 18(4):313-9. PMID: 15846157.
      View in: PubMed
    45. Yu Q, Shen Y, Chatterjee B, Siegfried BH, Leatherbury L, Rosenthal J, Lucas JF, Wessels A, Spurney CF, Wu YJ, Kirby ML, Svenson K, Lo CW. ENU induced mutations causing congenital cardiovascular anomalies. Development. 2004 Dec; 131(24):6211-23. PMID: 15548583.
      View in: PubMed
    46. Spurney CF, Leatherbury L, Lo CW. High-frequency ultrasound database profiling growth, development, and cardiovascular function in C57BL/6J mouse fetuses. J Am Soc Echocardiogr. 2004 Aug; 17(8):893-900. PMID: 15282495.
      View in: PubMed
    Spurney's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    Co-Authors Expand Description
    Similar People Expand Description
    Same Department Expand Description
    Physical Neighbors Expand Description