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Last Name
Institution

Freishtat, Robert

TitleAssociate Professor
InstitutionChildrens National Medical Center
DepartmentEmergency Medicine
Address111 Michigan Ave NW
Washington DC 20010
Phone(202) 476-2971
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pérez-Losada M, Graham RJ, Coquillette M, Jafarey A, Castro-Nallar E, Aira M, Hoptay C, Freishtat RJ, Mansbach JM. Tracheal Microbiota in Patients With a Tracheostomy Before, During and After an Acute Respiratory Infection. Pediatr Infect Dis J. 2018 Nov; 37(11):e269-e271. PMID: 29462107.
      View in: PubMed
    2. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Lindsell CJ. Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response. Crit Care Med. 2018 Mar; 46(3):e242-e249. PMID: 29252929.
      View in: PubMed
    3. Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR. Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. Pediatr Crit Care Med. 2018 Feb; 19(2):155-160. PMID: 29394222.
      View in: PubMed
    4. Hasegawa K, Pérez-Losada M, Hoptay CE, Epstein S, Mansbach JM, Teach SJ, Piedra PA, Camargo CA, Freishtat RJ. RSV vs. rhinovirus bronchiolitis: difference in nasal airway microRNA profiles and NF?B signaling. Pediatr Res. 2018 03; 83(3):606-614. PMID: 29244796.
      View in: PubMed
    5. Hahn A, Warnken S, Pérez-Losada M, Freishtat RJ, Crandall KA. Microbial diversity within the airway microbiome in chronic pediatric lung diseases. Infect Genet Evol. 2018 Sep; 63:316-325. PMID: 29225146.
      View in: PubMed
    6. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Lindsell CJ. Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP. Am J Respir Crit Care Med. 2017 08 15; 196(4):494-501. PMID: 28324661.
      View in: PubMed
    7. Pérez-Losada M, Graham RJ, Coquillette M, Jafarey A, Castro-Nallar E, Aira M, Freishtat RJ, Mansbach JM. The temporal dynamics of the tracheal microbiome in tracheostomised patients with and without lower respiratory infections. PLoS One. 2017; 12(8):e0182520. PMID: 28796800.
      View in: PubMed
    8. L'Yi S, Jung D, Oh M, Kim B, Freishtat RJ, Giri M, Hoffman E, Seo J. miRTarVis+: Web-based interactive visual analytics tool for microRNA target predictions. Methods. 2017 07 15; 124:78-88. PMID: 28600227.
      View in: PubMed
    9. Bartel S, Schulz N, Alessandrini F, Schamberger AC, Pagel P, Theis FJ, Milger K, Noessner E, Stick SM, Kicic A, Eickelberg O, Freishtat RJ, Krauss-Etschmann S. Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma. Sci Rep. 2017 04 06; 7:46026. PMID: 28383034.
      View in: PubMed
    10. Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Opoka A, Wong HR. Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock. Pediatr Crit Care Med. 2017 Apr; 18(4):299-303. PMID: 28178077.
      View in: PubMed
    11. Hackett TL, Ferrante SC, Hoptay CE, Engelhardt JF, Ingram JL, Zhang Y, Alcala SE, Shaheen F, Matz E, Pillai DK, Freishtat RJ. A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma. Am J Respir Cell Mol Biol. 2017 03; 56(3):291-299. PMID: 27788019.
      View in: PubMed
    12. Pérez-Losada M, Alamri L, Crandall KA, Freishtat RJ. Nasopharyngeal Microbiome Diversity Changes over Time in Children with Asthma. PLoS One. 2017; 12(1):e0170543. PMID: 28107528.
      View in: PubMed
    13. Hubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ. Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Obesity (Silver Spring). 2017 01; 25(1):102-110. PMID: 27883272.
      View in: PubMed
    14. Hasegawa K, Mansbach JM, Ajami NJ, Petrosino JF, Freishtat RJ, Teach SJ, Piedra PA, Camargo CA. Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis. J Allergy Clin Immunol. 2017 04; 139(4):1383-1386.e6. PMID: 27845236.
      View in: PubMed
    15. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Nguyen TC, Lindsell CJ. Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype. Crit Care Med. 2016 Nov; 44(11):2010-2017. PMID: 27513537.
      View in: PubMed
    16. Patregnani J, Klugman D, Zurakowski D, Sinha P, Freishtat R, Berger J, Diab Y. High on Aspirin Platelet Reactivity in Pediatric Patients Undergoing the Fontan Procedure. Circulation. 2016 10 25; 134(17):1303-1305. PMID: 27777299.
      View in: PubMed
    17. Wong HR, Atkinson SJ, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Lindsell CJ. Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids. Crit Care Med. 2016 10; 44(10):e1000-3. PMID: 27270179.
      View in: PubMed
    18. Gutierrez MJ, Gomez JL, Perez GF, Pancham K, Val S, Pillai DK, Giri M, Ferrante S, Freishtat R, Rose MC, Preciado D, Nino G. Airway Secretory microRNAome Changes during Rhinovirus Infection in Early Childhood. PLoS One. 2016; 11(9):e0162244. PMID: 27643599.
      View in: PubMed
    19. Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ. The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act. Ann Am Thorac Soc. 2016 08; 13(8):1205-7. PMID: 27509147.
      View in: PubMed
    20. Pérez-Losada M, Crandall KA, Freishtat RJ. Two sampling methods yield distinct microbial signatures in the nasopharynges of asthmatic children. Microbiome. 2016 Jun 16; 4(1):25. PMID: 27306800.
      View in: PubMed
    21. Maltz L, Matz EL, Gordish-Dressman H, Pillai DK, Teach SJ, Camargo CA, Hubal MJ, Behniwal S, Prosper GD, Certner N, Marwah R, Mansell DM, Nwachukwu F, Lazaroff R, Tsegaye Y, Freishtat RJ. Sex differences in the association between neck circumference and asthma. Pediatr Pulmonol. 2016 09; 51(9):893-900. PMID: 26774073.
      View in: PubMed
    22. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Lindsell CJ. Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology. EBioMedicine. 2015 Dec; 2(12):2087-93. PMID: 26844289; PMCID: PMC4703723.
      View in: PubMed, PubMed Central
    23. Freishtat RJ, Nino G, Tsegaye Y, Alcala SE, Benton AS, Watson AM, Reeves EK, Haider SK, Damsker JM. Pharmacologically-induced mitotic synchrony in airway epithelial cells as a mechanism of action of anti-inflammatory drugs. Respir Res. 2015 Oct 29; 16:132. PMID: 26511361; PMCID: PMC4625853.
      View in: PubMed, PubMed Central
    24. Grunwell JR, Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Howard K, Frank E, Harmon K, Wong HR. Differential expression of the Nrf2-linked genes in pediatric septic shock. Crit Care. 2015 Sep 17; 19:327. PMID: 26376786; PMCID: PMC4574004.
      View in: PubMed, PubMed Central
    25. Castro-Nallar E, Shen Y, Freishtat RJ, Pérez-Losada M, Manimaran S, Liu G, Johnson WE, Crandall KA. Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities. BMC Med Genomics. 2015 Aug 16; 8:50. PMID: 26277095; PMCID: PMC4537781.
      View in: PubMed, PubMed Central
    26. Jung D, Kim B, Freishtat RJ, Giri M, Hoffman E, Seo J. miRTarVis: an interactive visual analysis tool for microRNA-mRNA expression profile data. BMC Proc. 2015; 9(Suppl 6 Proceedings of the 5th Symposium on Biological Data):S2. PMID: 26361498; PMCID: PMC4547149.
      View in: PubMed, PubMed Central
    27. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Dawson E, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Lindsell CJ. A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med. 2015 Aug; 43(8):1646-53. PMID: 25962083; PMCID: PMC4667777.
      View in: PubMed, PubMed Central
    28. Pérez-Losada M, Castro-Nallar E, Bendall ML, Freishtat RJ, Crandall KA. Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma. PLoS One. 2015; 10(6):e0131819. PMID: 26125632; PMCID: PMC4488395.
      View in: PubMed, PubMed Central
    29. Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ. Developing a clinically feasible personalized medicine approach to pediatric septic shock. Am J Respir Crit Care Med. 2015 Feb 01; 191(3):309-15. PMID: 25489881; PMCID: PMC4351580.
      View in: PubMed, PubMed Central
    30. Meyer AD, Gelfond JA, Wiles AA, Freishtat RJ, Rais-Bahrami K. Platelet-derived microparticles generated by neonatal extracorporeal membrane oxygenation systems. ASAIO J. 2015 Jan-Feb; 61(1):37-42. PMID: 25303795; PMCID: PMC4628788.
      View in: PubMed, PubMed Central
    31. Ferrante SC, Nadler EP, Pillai DK, Hubal MJ, Wang Z, Wang JM, Gordish-Dressman H, Koeck E, Sevilla S, Wiles AA, Freishtat RJ. Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease. Pediatr Res. 2015 Mar; 77(3):447-54. PMID: 25518011; PMCID: PMC4346410.
      View in: PubMed, PubMed Central
    32. Tat ST, Mejia MJ, Freishtat RJ. Imaging, clearance, and controversies in pediatric cervical spine trauma. Pediatr Emerg Care. 2014 Dec; 30(12):911-5; quiz 916-8. PMID: 25469605.
      View in: PubMed
    33. Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Wong HR. Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock. Crit Care. 2014 Nov 19; 18(6):623. PMID: 25410281; PMCID: PMC4247726.
      View in: PubMed, PubMed Central
    34. Atkinson SJ, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Weiss SL, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Lahni P, Lindsell CJ, Wong HR. Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis. PLoS One. 2014; 9(11):e112702. PMID: 25386653; PMCID: PMC4227847.
      View in: PubMed, PubMed Central
    35. Dadgar S, Wang Z, Johnston H, Kesari A, Nagaraju K, Chen YW, Hill DA, Partridge TA, Giri M, Freishtat RJ, Nazarian J, Xuan J, Wang Y, Hoffman EP. Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy. J Cell Biol. 2014 Oct 13; 207(1):139-58. PMID: 25313409; PMCID: PMC4195829.
      View in: PubMed, PubMed Central
    36. Alcala SE, Benton AS, Watson AM, Kureshi S, Reeves EM, Damsker J, Wang Z, Nagaraju K, Anderson J, Williams AM, Lee AJ, Hayes K, Rose MC, Hoffman EP, Freishtat RJ. Mitotic asynchrony induces transforming growth factor-ß1 secretion from airway epithelium. Am J Respir Cell Mol Biol. 2014 Sep; 51(3):363-9. PMID: 24669775; PMCID: PMC4189490.
      View in: PubMed, PubMed Central
    37. Koeck ES, Iordanskaia T, Sevilla S, Ferrante SC, Hubal MJ, Freishtat RJ, Nadler EP. Adipocyte exosomes induce transforming growth factor beta pathway dysregulation in hepatocytes: a novel paradigm for obesity-related liver disease. J Surg Res. 2014 Dec; 192(2):268-75. PMID: 25086727.
      View in: PubMed
    38. Rao AK, Freishtat RJ, Jalagadugula G, Singh A, Mao G, Wiles A, Cheung P, Boden G. Alterations in insulin-signaling and coagulation pathways in platelets during hyperglycemia-hyperinsulinemia in healthy non-diabetic subject. Thromb Res. 2014 Sep; 134(3):704-10. PMID: 25042561.
      View in: PubMed
    39. Fu L, Freishtat RJ, Gordish-Dressman H, Teach SJ, Resca L, Hoffman EP, Wang Z. Natural progression of childhood asthma symptoms and strong influence of sex and puberty. Ann Am Thorac Soc. 2014 Jul; 11(6):939-44. PMID: 24896645; PMCID: PMC4213994.
      View in: PubMed, PubMed Central
    40. Perez GF, Pancham K, Huseni S, Preciado D, Freishtat RJ, Colberg-Poley AM, Hoffman EP, Rose MC, Nino G. Rhinovirus infection in young children is associated with elevated airway TSLP levels. Eur Respir J. 2014 Oct; 44(4):1075-8. PMID: 24969655; PMCID: PMC4183718.
      View in: PubMed, PubMed Central
    41. Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Weiss SL, Shanley TP, Bigham MT, Banschbach S, Beckman E, Harmon K, Zimmerman JJ. Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med. 2014 Apr 15; 189(8):940-6. PMID: 24650276; PMCID: PMC4098101.
      View in: PubMed, PubMed Central
    42. Wong HR, Weiss SL, Giuliano JS, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Harmon K, Lahni P, Lindsell CJ. The temporal version of the pediatric sepsis biomarker risk model. PLoS One. 2014; 9(3):e92121. PMID: 24626215; PMCID: PMC3953585.
      View in: PubMed, PubMed Central
    43. Abulebda K, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Weiss SL, Chopra A, Banschbach S, Beckman E, Lindsell CJ, Wong HR. Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis. Crit Care Med. 2014 Feb; 42(2):397-403. PMID: 24145842; PMCID: PMC3947064.
      View in: PubMed, PubMed Central
    44. Wong HR, Weiss SL, Giuliano JS, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Lahni P, Hart K, Lindsell CJ. Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model. PLoS One. 2014; 9(1):e86242. PMID: 24489704; PMCID: PMC3906040.
      View in: PubMed, PubMed Central
    45. Iqbal S, Mosenkis EV, Jain P, Wiles A, Lerner J, Benton AS, Chamberlain JM, Freishtat RJ, Teach SJ. Vitamin d in pediatric inpatients with respiratory illnesses. Hosp Pediatr. 2013 Oct; 3(4):371-6. PMID: 24435196.
      View in: PubMed
    46. Damsker JM, Dillingham BC, Rose MC, Balsley MA, Heier CR, Watson AM, Stemmy EJ, Jurjus RA, Huynh T, Tatem K, Uaesoontrachoon K, Berry DM, Benton AS, Freishtat RJ, Hoffman EP, McCall JM, Gordish-Dressman H, Constant SL, Reeves EK, Nagaraju K. VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice. PLoS One. 2013; 8(5):e63871. PMID: 23667681; PMCID: PMC3646769.
      View in: PubMed, PubMed Central
    47. Wong HR, Cvijanovich NZ, Hall M, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Bigham MT, Sen A, Nowak J, Quasney M, Henricksen JW, Chopra A, Banschbach S, Beckman E, Harmon K, Lahni P, Shanley TP. Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children. Crit Care. 2012 Oct 29; 16(5):R213. PMID: 23107287; PMCID: PMC3682317.
      View in: PubMed, PubMed Central
    48. Wong HR, Salisbury S, Xiao Q, Cvijanovich NZ, Hall M, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Sen A, Nowak J, Quasney M, Henricksen JW, Chopra A, Banschbach S, Beckman E, Harmon K, Lahni P, Lindsell CJ. The pediatric sepsis biomarker risk model. Crit Care. 2012 Oct 01; 16(5):R174. PMID: 23025259; PMCID: PMC3682273.
      View in: PubMed, PubMed Central
    49. Ryan LM, Teach SJ, Singer SA, Wood R, Freishtat R, Wright JL, McCarter R, Tosi L, Chamberlain JM. Bone mineral density and vitamin D status among African American children with forearm fractures. Pediatrics. 2012 Sep; 130(3):e553-60. PMID: 22926174.
      View in: PubMed
    50. Ryan LM, Chamberlain JM, Singer SA, Wood R, Tosi LL, Freishtat RJ, Gordish-Dressman H, Teach SJ, Devaney JM. Genetic influences on vitamin D status and forearm fracture risk in African American children. J Investig Med. 2012 Aug; 60(6):902-6. PMID: 22613962; PMCID: PMC3404230.
      View in: PubMed, PubMed Central
    51. Sharron M, Hoptay CE, Wiles AA, Garvin LM, Geha M, Benton AS, Nagaraju K, Freishtat RJ. Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade. PLoS One. 2012; 7(7):e41549. PMID: 22844498.
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    52. Meyer AD, Wiles AA, Rivera O, Wong EC, Freishtat RJ, Rais-Bahrami K, Dalton HJ. Hemolytic and thrombocytopathic characteristics of extracorporeal membrane oxygenation systems at simulated flow rate for neonates. Pediatr Crit Care Med. 2012 Jul; 13(4):e255-61. PMID: 22596067; PMCID: PMC3477222.
      View in: PubMed, PubMed Central
    53. Payne AS, Freishtat RJ. Conserved steroid hormone homology converges on nuclear factor ?B to modulate inflammation in asthma. J Investig Med. 2012 Jan; 60(1):13-7. PMID: 22183120; PMCID: PMC3335887.
      View in: PubMed, PubMed Central
    54. Iqbal SF, Freishtat RJ. Mechanism of action of vitamin D in the asthmatic lung. J Investig Med. 2011 Dec; 59(8):1200-2. PMID: 21941209; PMCID: PMC3238450.
      View in: PubMed, PubMed Central
    55. Basu RK, Standage SW, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Devarajan P, Goldstein SL, Wong HR. Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray. Crit Care. 2011; 15(6):R273. PMID: 22098946; PMCID: PMC3388679.
      View in: PubMed, PubMed Central
    56. Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Doughty LA, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Varisco BM, Barr FE. Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med. 2011 Nov; 39(11):2511-7. PMID: 21705885; PMCID: PMC3196776.
      View in: PubMed, PubMed Central
    57. Stemmy EJ, Benton AS, Lerner J, Alcala S, Constant SL, Freishtat RJ. Extracellular cyclophilin levels associate with parameters of asthma in phenotypic clusters. J Asthma. 2011 Dec; 48(10):986-993. PMID: 21999750; PMCID: PMC4046105.
      View in: PubMed, PubMed Central
    58. Pillai DK, Iqbal SF, Benton AS, Lerner J, Wiles A, Foerster M, Ozedirne T, Holbrook HP, Payne PW, Gordish-Dressman H, Teach SJ, Freishtat RJ. Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans: a pilot study. J Investig Med. 2011 Aug; 59(6):938-46. PMID: 21613960; PMCID: PMC3199964.
      View in: PubMed, PubMed Central
    59. Wynn JL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Banschbach S, Beckman E, Wong HR. The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med. 2011; 17(11-12):1146-56. PMID: 21738952.
      View in: PubMed
    60. Benton AS, Kumar N, Lerner J, Wiles AA, Foerster M, Teach SJ, Freishtat RJ. Airway platelet activation is associated with airway eosinophilic inflammation in asthma. J Investig Med. 2010 Dec; 58(8):987-90. PMID: 20930644; PMCID: PMC3324858.
      View in: PubMed, PubMed Central
    61. Cohen JS, Benton AS, Nwachukwu F, Ozedirne T, Teach SJ, Freishtat RJ. P-glycoprotein transporter expression on a549 respiratory epithelial cells is positively correlated with intracellular dexamethasone levels. J Investig Med. 2010 Dec; 58(8):991-4. PMID: 20940624.
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    62. Benton AS, Wang Z, Lerner J, Foerster M, Teach SJ, Freishtat RJ. Overcoming heterogeneity in pediatric asthma: tobacco smoke and asthma characteristics within phenotypic clusters in an African American cohort. J Asthma. 2010 Sep; 47(7):728-34. PMID: 20684733; PMCID: PMC3325290.
      View in: PubMed, PubMed Central
    63. Freishtat RJ, Watson AM, Benton AS, Iqbal SF, Pillai DK, Rose MC, Hoffman EP. Asthmatic airway epithelium is intrinsically inflammatory and mitotically dyssynchronous. Am J Respir Cell Mol Biol. 2011 Jun; 44(6):863-9. PMID: 20705942; PMCID: PMC3135846.
      View in: PubMed, PubMed Central
    64. Watson AM, Benton AS, Rose MC, Freishtat RJ. Cigarette smoke alters tissue inhibitor of metalloproteinase 1 and matrix metalloproteinase 9 levels in the basolateral secretions of human asthmatic bronchial epithelium in vitro. J Investig Med. 2010 Jun; 58(5):725-9. PMID: 20305574; PMCID: PMC3325291.
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    65. Wong HR, Freishtat RJ, Monaco M, Odoms K, Shanley TP. Leukocyte subset-derived genomewide expression profiles in pediatric septic shock. Pediatr Crit Care Med. 2010 May; 11(3):349-55. PMID: 20009785; PMCID: PMC2927840.
      View in: PubMed, PubMed Central
    66. Freishtat RJ, Iqbal SF, Pillai DK, Klein CJ, Ryan LM, Benton AS, Teach SJ. High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC. J Pediatr. 2010 Jun; 156(6):948-952. PMID: 20236657.
      View in: PubMed
    67. Ryan LM, Brandoli C, Freishtat RJ, Wright JL, Tosi L, Chamberlain JM. Prevalence of vitamin D insufficiency in African American children with forearm fractures: a preliminary study. J Pediatr Orthop. 2010 Mar; 30(2):106-9. PMID: 20179554.
      View in: PubMed
    68. Freishtat RJ, Nagaraju K, Jusko W, Hoffman EP. Glucocorticoid efficacy in asthma: is improved tissue remodeling upstream of anti-inflammation. J Investig Med. 2010 Jan; 58(1):19-22. PMID: 19730133; PMCID: PMC3324850.
      View in: PubMed, PubMed Central
    69. Watson AM, Ngor WM, Gordish-Dressman H, Freishtat RJ, Rose MC. MUC7 polymorphisms are associated with a decreased risk of a diagnosis of asthma in an African American population. J Investig Med. 2009 Dec; 57(8):882-6. PMID: 19820409; PMCID: PMC3326394.
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    70. Freishtat RJ, Benton AS, Watson AM, Wang Z, Rose MC, Hoffman EP. Delineation of a gene network underlying the pulmonary response to oxidative stress in asthma. J Investig Med. 2009 Oct; 57(7):756-64. PMID: 19730131; PMCID: PMC3328512.
      View in: PubMed, PubMed Central
    71. Wong HR, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Willson DF, Freishtat RJ, Anas N, Meyer K, Checchia PA, Monaco M, Odom K, Shanley TP. Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med. 2009 Jul 22; 7:34. PMID: 19624809; PMCID: PMC2720987.
      View in: PubMed, PubMed Central
    72. Zaveri PP, Morris DM, Freishtat RJ, Brown K. Overweight children: are they at increased risk for severe injury in motor vehicle collisions? Accid Anal Prev. 2009 Sep; 41(5):959-62. PMID: 19664432.
      View in: PubMed
    73. Wong HR, Cvijanovich N, Allen GL, Lin R, Anas N, Meyer K, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Shanley TP. Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum. Crit Care Med. 2009 May; 37(5):1558-66. PMID: 19325468; PMCID: PMC2747356.
      View in: PubMed, PubMed Central
    74. Freishtat RJ, Natale J, Benton AS, Cohen J, Sharron M, Wiles AA, Ngor WM, Mojgani B, Bradbury M, Degnan A, Sachdeva R, Debiase LM, Ghimbovschi S, Chow M, Bunag C, Kristosturyan E, Hoffman EP. Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity. Am J Respir Crit Care Med. 2009 Mar 15; 179(6):467-73. PMID: 19136373; PMCID: PMC2654976.
      View in: PubMed, PubMed Central
    75. Cvijanovich N, Shanley TP, Lin R, Allen GL, Thomas NJ, Checchia P, Anas N, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Wong HR. Validating the genomic signature of pediatric septic shock. Physiol Genomics. 2008 Jun 12; 34(1):127-34. PMID: 18460642; PMCID: PMC2440641.
      View in: PubMed, PubMed Central
    76. Freishtat RJ, Mojgani B, Mathison DJ, Chamberlain JM. Toward early identification of acute lung injury in the emergency department. J Investig Med. 2007 Dec; 55(8):423-9. PMID: 18163968; PMCID: PMC2214900.
      View in: PubMed, PubMed Central
    77. Freishtat RJ, Mojgani B, Nazemzadeh M, Nagaraju K, Hoffman EP. NKG2A inhibits TH2 cell effector function in vitro. BMC Pulm Med. 2007 Oct 10; 7:14. PMID: 17927829; PMCID: PMC2174509.
      View in: PubMed, PubMed Central
    78. Freishtat RJ, Mitchell LW, Ghimbovschi SD, Meyers SB, Hoffman EP. NKG2A and CD56 are coexpressed on activated TH2 but not TH1 lymphocytes. Hum Immunol. 2005 Dec; 66(12):1223-34. PMID: 16690409; PMCID: PMC1851905.
      View in: PubMed, PubMed Central
    79. Freishtat RJ, Teach SJ. Understanding genomics: implications for the emergency medicine physician and the treatment of asthma. Pediatr Emerg Care. 2006 Jan; 22(1):71-5; quiz 76-8. PMID: 16418618; PMCID: PMC2080853.
      View in: PubMed, PubMed Central
    80. Freishtat RJ, Chamberlain JM, Johns CM, Teach SJ, Ronzio C, Murphy-Smith MM, Gor N. A cross-sectional ED survey of infantile subclinical methemoglobinemia. Am J Emerg Med. 2005 Jul; 23(4):574-6. PMID: 16032641; PMCID: PMC2771727.
      View in: PubMed, PubMed Central
    81. Freishtat RJ, Klein BL, Teach SJ, Johns CM, Arapian LS, Perraut ME, Chamberlain JM. Admission predictor modeling in pediatric interhospital transport. Pediatr Emerg Care. 2004 Jul; 20(7):443-7. PMID: 15232244.
      View in: PubMed
    82. Freishtat RJ, Goepp JG. Episodic stridor with latex nipple use in a 2-month-old infant. Ann Emerg Med. 2002 Apr; 39(4):441-3. PMID: 11919533.
      View in: PubMed
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