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Institution

Ladisch, Stephan

TitleProfessor
InstitutionChildrens National Medical Center
DepartmentCenter for Cancer and Immunology
Address111 Michigan Ave NW
Washington DC 20010
Phone(202) 4763883
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Allen CE, Ladisch S, McClain KL. How I treat Langerhans cell histiocytosis. Blood. 2015 Jul 02; 126(1):26-35. PMID: 25827831; PMCID: PMC4492195.
    2. Aricò M, Astigarraga I, Braier J, Donadieu J, Gadner H, Glogova E, Grois N, Henter JI, Janka G, McClain KL, Ladisch S, Pötschger U, Rosso D, Thiem E, Weitzman S, Windebank K, Minkov M. Lack of bone lesions at diagnosis is associated with inferior outcome in multisystem langerhans cell histiocytosis of childhood. Br J Haematol. 2015 Apr; 169(2):241-8. PMID: 25522229.
      View in: PubMed
    3. Wondimu A, Liu Y, Su Y, Bobb D, Ma JS, Chakrabarti L, Radoja S, Ladisch S. Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells. Cancer Res. 2014 Oct 01; 74(19):5449-57. PMID: 25115301; PMCID: PMC4184983.
    4. Ladisch S, Liu Y. Dynamic aspects of neural tumor gangliosides. Adv Neurobiol. 2014; 9:501-15. PMID: 25151394.
      View in: PubMed
    5. Liu Y, Wondimu A, Yan S, Bobb D, Ladisch S. Tumor gangliosides accelerate murine tumor angiogenesis. Angiogenesis. 2014 Jul; 17(3):563-71. PMID: 24165965; PMCID: PMC4004731.
    6. Gadner H, Minkov M, Grois N, Pötschger U, Thiem E, Aricò M, Astigarraga I, Braier J, Donadieu J, Henter JI, Janka-Schaub G, McClain KL, Weitzman S, Windebank K, Ladisch S. Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis. Blood. 2013 Jun 20; 121(25):5006-14. PMID: 23589673.
      View in: PubMed
    7. Lee HC, Wondimu A, Liu Y, Ma JS, Radoja S, Ladisch S. Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J Immunol. 2012 Oct 01; 189(7):3521-7. PMID: 22956583.
      View in: PubMed
    8. Trottestam H, Horne A, Aricò M, Egeler RM, Filipovich AH, Gadner H, Imashuku S, Ladisch S, Webb D, Janka G, Henter JI. Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol. Blood. 2011 Oct 27; 118(17):4577-84. PMID: 21900192; PMCID: PMC3208276.
    9. Dong L, Liu Y, Colberg-Poley AM, Kaucic K, Ladisch S. Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function. Glycoconj J. 2011 May; 28(3-4):137-47. PMID: 21519903; PMCID: PMC3107379.
    10. Jales A, Falahati R, Mari E, Stemmy EJ, Shen W, Southammakosane C, Herzog D, Ladisch S, Leitenberg D. Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity. Immunology. 2011 Jan; 132(1):134-43. PMID: 20875076; PMCID: PMC3015083.
    11. Weitzman S, Braier J, Donadieu J, Egeler RM, Grois N, Ladisch S, Pötschger U, Webb D, Whitlock J, Arceci RJ. 2'-Chlorodeoxyadenosine (2-CdA) as salvage therapy for Langerhans cell histiocytosis (LCH). results of the LCH-S-98 protocol of the Histiocyte Society. Pediatr Blood Cancer. 2009 Dec 15; 53(7):1271-6. PMID: 19731321.
      View in: PubMed
    12. Minkov M, Steiner M, Pötschger U, Aricò M, Braier J, Donadieu J, Grois N, Henter JI, Janka G, McClain K, Weitzman S, Windebank K, Ladisch S, Gadner H. Reactivations in multisystem Langerhans cell histiocytosis: data of the international LCH registry. J Pediatr. 2008 Nov; 153(5):700-5, 705.e1-2. PMID: 18589441.
      View in: PubMed
    13. Liu Y, Su Y, Wiznitzer M, Epifano O, Ladisch S. Ganglioside depletion and EGF responses of human GM3 synthase-deficient fibroblasts. Glycobiology. 2008 Aug; 18(8):593-601. PMID: 18480157.
      View in: PubMed
    14. Shen W, Stone K, Jales A, Leitenberg D, Ladisch S. Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. J Immunol. 2008 Apr 01; 180(7):4425-32. PMID: 18354163.
      View in: PubMed
    15. Gadner H, Grois N, Pötschger U, Minkov M, Aricò M, Braier J, Broadbent V, Donadieu J, Henter JI, McCarter R, Ladisch S. Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification. Blood. 2008 Mar 01; 111(5):2556-62. PMID: 18089850.
      View in: PubMed
    16. Horne A, Trottestam H, Aricò M, Egeler RM, Filipovich AH, Gadner H, Imashuku S, Ladisch S, Webb D, Janka G, Henter JI. Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis. Br J Haematol. 2008 Feb; 140(3):327-35. PMID: 18076710.
      View in: PubMed
    17. Shevchuk NA, Hathout Y, Epifano O, Su Y, Liu Y, Sutherland M, Ladisch S. Alteration of ganglioside synthesis by GM3 synthase knockout in murine embryonic fibroblasts. Biochim Biophys Acta. 2007 Sep; 1771(9):1226-34. PMID: 17604219.
      View in: PubMed
    18. Henter JI, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007 Feb; 48(2):124-31. PMID: 16937360.
      View in: PubMed
    19. De Clerck YA, Weissman BE, Yu D, Parsons R, Bar-Eli M, Roy-Burman P, Seewaldt VL, Cress AE, Languino LR, Batra SK, Tang CK, Sheng S, Chen WT, Chellappan S, Cheng SY, Ladisch S, McCarthy JB, Coussens LM, Cohen MB. Tumor progression and metastasis from genetic to microenvironmental determinants: a workshop of the tumor progression and metastasis NIH study section in honor of Dr. Martin L. Padarathsingh, May 31, 2006, Georgetown, Washington, DC. Cancer Biol Ther. 2006 Dec; 5(12):1588-99. PMID: 17224636.
      View in: PubMed
    20. Liu Y, McCarthy J, Ladisch S. Membrane ganglioside enrichment lowers the threshold for vascular endothelial cell angiogenic signaling. Cancer Res. 2006 Nov 01; 66(21):10408-14. PMID: 17079461.
      View in: PubMed
    21. Kaucic K, Liu Y, Ladisch S. Modulation of growth factor signaling by gangliosides: positive or negative? Methods Enzymol. 2006; 417:168-85. PMID: 17132505; PMCID: PMC2852130.
    22. Shen W, Falahati R, Stark R, Leitenberg D, Ladisch S. Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. J Immunol. 2005 Oct 15; 175(8):4927-34. PMID: 16210594.
      View in: PubMed
    23. Horne A, Janka G, Maarten Egeler R, Gadner H, Imashuku S, Ladisch S, Locatelli F, Montgomery SM, Webb D, Winiarski J, Filipovich AH, Henter JI. Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis. Br J Haematol. 2005 Jun; 129(5):622-30. PMID: 15916685.
      View in: PubMed
    24. Hainz U, Obexer P, Winkler C, Sedlmayr P, Takikawa O, Greinix H, Lawitschka A, Pötschger U, Fuchs D, Ladisch S, Heitger A. Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation. Blood. 2005 May 15; 105(10):4127-34. PMID: 15677560; PMCID: PMC1895091.
    25. Hettmer S, Ladisch S, Kaucic K. Low complex ganglioside expression characterizes human neuroblastoma cell lines. Cancer Lett. 2005 Jul 08; 225(1):141-9. PMID: 15922866; PMCID: PMC2866625.
    26. Liu Y, Li R, Ladisch S. Exogenous ganglioside GD1a enhances epidermal growth factor receptor binding and dimerization. J Biol Chem. 2004 Aug 27; 279(35):36481-9. PMID: 15215248.
      View in: PubMed
    27. Shevchuk NA, Bryksin AV, Nusinovich YA, Cabello FC, Sutherland M, Ladisch S. Construction of long DNA molecules using long PCR-based fusion of several fragments simultaneously. Nucleic Acids Res. 2004 Jan 22; 32(2):e19. PMID: 14739232; PMCID: PMC373371.
    28. Guerrera M, Ladisch S. N-butyldeoxynojirimycin inhibits murine melanoma cell ganglioside metabolism and delays tumor onset. Cancer Lett. 2003 Nov 10; 201(1):31-40. PMID: 14580684.
      View in: PubMed
    29. Hettmer S, Malott C, Woods W, Ladisch S, Kaucic K. Biological stratification of human neuroblastoma by complex "B" pathway ganglioside expression. Cancer Res. 2003 Nov 01; 63(21):7270-6. PMID: 14612523.
      View in: PubMed
    30. Caldwell S, Heitger A, Shen W, Liu Y, Taylor B, Ladisch S. Mechanisms of ganglioside inhibition of APC function. J Immunol. 2003 Aug 15; 171(4):1676-83. PMID: 12902465; PMCID: PMC2849639.
    31. Weiss M, Hettmer S, Smith P, Ladisch S. Inhibition of melanoma tumor growth by a novel inhibitor of glucosylceramide synthase. Cancer Res. 2003 Jul 01; 63(13):3654-8. PMID: 12839955.
      View in: PubMed
    32. Minkov M, Grois N, Braier J, Rosso D, Aricò M, Broadbent V, Gadner H, Ladisch S. Immunosuppressive treatment for chemotherapy-resistant multisystem Langerhans cell histiocytosis. Med Pediatr Oncol. 2003 Apr; 40(4):253-6. PMID: 12555257.
      View in: PubMed
    33. Shen W, Ladisch S. Ganglioside GD1a impedes lipopolysaccharide-induced maturation of human dendritic cells. Cell Immunol. 2002 Dec; 220(2):125-33. PMID: 12657247.
      View in: PubMed
    34. Henter JI, Samuelsson-Horne A, Aricò M, Egeler RM, Elinder G, Filipovich AH, Gadner H, Imashuku S, Komp D, Ladisch S, Webb D, Janka G. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002 Oct 01; 100(7):2367-73. PMID: 12239144.
      View in: PubMed
    35. Deng W, Li R, Guerrera M, Liu Y, Ladisch S. Transfection of glucosylceramide synthase antisense inhibits mouse melanoma formation. Glycobiology. 2002 Mar; 12(3):145-52. PMID: 11971858.
      View in: PubMed
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