 Mucin 5AC
"Mucin 5AC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gel-forming mucin that is primarily found on the surface of gastric epithelium and in the RESPIRATORY TRACT. Mucin 5AC was originally identified as two distinct proteins, however a single gene encodes the protein which gives rise to the mucin 5A and mucin 5C variants.
| Descriptor ID |
D055271
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| MeSH Number(s) |
D12.776.395.560.631.100.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucin 5AC".
Below are MeSH descriptors whose meaning is more specific than "Mucin 5AC".
This graph shows the total number of publications written about "Mucin 5AC" by people in this website by year, and whether "Mucin 5AC" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Mucin 5AC" by people in Profiles.
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Duah V, Huang Z, Val S, DeMason C, Poley M, Preciado D. Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B. Int J Pediatr Otorhinolaryngol. 2016 Nov; 90:133-137.
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Garvin LM, Chen Y, Damsker JM, Rose MC. A novel dissociative steroid VBP15 reduces MUC5AC gene expression in airway epithelial cells but lacks the GRE mediated transcriptional properties of dexamethasone. Pulm Pharmacol Ther. 2016 06; 38:17-26.
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Val S, Kwon HJ, Rose MC, Preciado D. Middle Ear Response of Muc5ac and Muc5b Mucins to Nontypeable Haemophilus influenzae. JAMA Otolaryngol Head Neck Surg. 2015 Nov; 141(11):997-1005.
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Chen Y, Garvin LM, Nickola TJ, Watson AM, Colberg-Poley AM, Rose MC. IL-1ß induction of MUC5AC gene expression is mediated by CREB and NF-?B and repressed by dexamethasone. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 15; 306(8):L797-807.
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Chen Y, Watson AM, Williamson CD, Rahimi M, Liang C, Colberg-Poley AM, Rose MC. Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression. Am J Respir Cell Mol Biol. 2012 Nov; 47(5):637-44.
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Wu X, Amorn MM, Aujla PK, Rice S, Mimms R, Watson AM, Peters-Hall JR, Rose MC, Peña MT. Histologic characteristics and mucin immunohistochemistry of cystic fibrosis sinus mucosa. Arch Otolaryngol Head Neck Surg. 2011 Apr; 137(4):383-9.
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Bautista MV, Chen Y, Ivanova VS, Rahimi MK, Watson AM, Rose MC. IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells. J Immunol. 2009 Aug 01; 183(3):2159-66.
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Peña MT, Aujla PK, Patel KM, Zalzal GH, Rose MC. Immunohistochemical analyses of MUC5AC mucin expression in sinus mucosa of children with sinusitis and controls. Ann Otol Rhinol Laryngol. 2005 Dec; 114(12):958-65.
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Chen Y, Nickola TJ, DiFronzo NL, Colberg-Poley AM, Rose MC. Dexamethasone-mediated repression of MUC5AC gene expression in human lung epithelial cells. Am J Respir Cell Mol Biol. 2006 Mar; 34(3):338-47.
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Shahzeidi S, Aujla PK, Nickola TJ, Chen Y, Alimam MZ, Rose MC. Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma. Exp Lung Res. 2003 Dec; 29(8):549-65.
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