 Vigabatrin
"Vigabatrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID. (From Martindale The Extra Pharmacopoeia, 31st ed)
| Descriptor ID |
D020888
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| MeSH Number(s) |
D02.241.081.114.500.350.900 D12.125.190.350.900
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| Concept/Terms |
Vigabatrin- Vigabatrin
- gamma-Vinyl-GABA
- gamma Vinyl GABA
- gamma-Vinyl-gamma-Aminobutyric Acid
- Acid, gamma-Vinyl-gamma-Aminobutyric
- gamma Vinyl gamma Aminobutyric Acid
Sabril- Sabril
- Yamanouchi Brand of Vigabatrin
- Vigabatrin Yamanouchi Brand
- Sabrilex
- Aventis Brand of Vigabatrin
- Vigabatrin Aventis Brand
- Hoechst Brand of Vigabatrin
- Vigabatrin Hoechst Brand
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Below are MeSH descriptors whose meaning is more general than "Vigabatrin".
Below are MeSH descriptors whose meaning is more specific than "Vigabatrin".
This graph shows the total number of publications written about "Vigabatrin" by people in this website by year, and whether "Vigabatrin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2010 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 3 | 0 | 3 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vigabatrin" by people in Profiles.
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Demarest ST, Shellhaas RA, Gaillard WD, Keator C, Nickels KC, Hussain SA, Loddenkemper T, Patel AD, Saneto RP, Wirrell E, Sánchez Fernández I, Chu CJ, Grinspan Z, Wusthoff CJ, Joshi S, Mohamed IS, Stafstrom CE, Stack CV, Yozawitz E, Bluvstein JS, Singh RK, Knupp KG. The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium. Epilepsia. 2017 12; 58(12):2098-2103.
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Knupp KG, Leister E, Coryell J, Nickels KC, Ryan N, Juarez-Colunga E, Gaillard WD, Mytinger JR, Berg AT, Millichap J, Nordli DR, Joshi S, Shellhaas RA, Loddenkemper T, Dlugos D, Wirrell E, Sullivan J, Hartman AL, Kossoff EH, Grinspan ZM, Hamikawa L. Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort. Epilepsia. 2016 11; 57(11):1834-1842.
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Origlieri C, Geddie B, Karwoski B, Berl MM, Elling N, McClintock W, Alexander J, Bazemore M, de Beaufort H, Hutcheson K, Miller M, Taylormoore J, Jaafar MS, Madigan W. Optical coherence tomography to monitor vigabatrin toxicity in children. J AAPOS. 2016 Apr; 20(2):136-40.
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Knupp KG, Coryell J, Nickels KC, Ryan N, Leister E, Loddenkemper T, Grinspan Z, Hartman AL, Kossoff EH, Gaillard WD, Mytinger JR, Joshi S, Shellhaas RA, Sullivan J, Dlugos D, Hamikawa L, Berg AT, Millichap J, Nordli DR, Wirrell E. Response to treatment in a prospective national infantile spasms cohort. Ann Neurol. 2016 Mar; 79(3):475-84.
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Zonouzi M, Scafidi J, Li P, McEllin B, Edwards J, Dupree JL, Harvey L, Sun D, Hübner CA, Cull-Candy SG, Farrant M, Gallo V. GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nat Neurosci. 2015 May; 18(5):674-82.
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Pellock JM, Hrachovy R, Shinnar S, Baram TZ, Bettis D, Dlugos DJ, Gaillard WD, Gibson PA, Holmes GL, Nordl DR, O'Dell C, Shields WD, Trevathan E, Wheless JW. Infantile spasms: a U.S. consensus report. Epilepsia. 2010 Oct; 51(10):2175-89.
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Hong AM, Turner Z, Hamdy RF, Kossoff EH. Infantile spasms treated with the ketogenic diet: prospective single-center experience in 104 consecutive infants. Epilepsia. 2010 Aug; 51(8):1403-7.
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Wheless JW, Carmant L, Bebin M, Conry JA, Chiron C, Elterman RD, Frost M, Paolicchi JM, Donald Shields W, Thiele EA, Zupanc ML, Collins SD. Magnetic resonance imaging abnormalities associated with vigabatrin in patients with epilepsy. Epilepsia. 2009 Feb; 50(2):195-205.
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Pearl PL, Vezina LG, Saneto RP, McCarter R, Molloy-Wells E, Heffron A, Trzcinski S, McClintock WM, Conry JA, Elling NJ, Goodkin HP, de Menezes MS, Ferri R, Gilles E, Kadom N, Gaillard WD. Cerebral MRI abnormalities associated with vigabatrin therapy. Epilepsia. 2009 Feb; 50(2):184-94.
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Conry JA. Pharmacologic treatment of the catastrophic epilepsies. Epilepsia. 2004; 45 Suppl 5:12-6.
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