I-kappa B Proteins
"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Descriptor ID |
D020672
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MeSH Number(s) |
D12.644.360.378 D12.776.260.420 D12.776.476.381 D12.776.930.326
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Concept/Terms |
I-kappa B Proteins- I-kappa B Proteins
- I kappa B Proteins
- IkB DNA-Binding Proteins
- IkB DNA Binding Proteins
- I kappa B
- I-kappa B
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Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".
This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 | 2002 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.
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Fernandez G, Zaikos TD, Khan SZ, Jacobi AM, Behlke MA, Zeichner SL. Targeting I?B proteins for HIV latency activation: the role of individual I?B and NF-?B proteins. J Virol. 2013 Apr; 87(7):3966-78.
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Preciado D, Caicedo E, Jhanjee R, Silver R, Harris G, Juhn SK, Choo DI, Ondrey F. Pseudomonas aeruginosa lipopolysaccharide induction of keratinocyte proliferation, NF-kappa B, and cyclin D1 is inhibited by indomethacin. J Immunol. 2005 Mar 01; 174(5):2964-73.
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Potoka DA, Upperman JS, Nadler EP, Wong CT, Zhou X, Zhang XR, Ford HR. NF-kappaB inhibition enhances peroxynitrite-induced enterocyte apoptosis. J Surg Res. 2002 Jul; 106(1):7-14.
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Ishibashi N, Weisbrot-Lefkowitz M, Reuhl K, Inouye M, Mirochnitchenko O. Modulation of chemokine expression during ischemia/reperfusion in transgenic mice overproducing human glutathione peroxidases. J Immunol. 1999 Nov 15; 163(10):5666-77.
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