Immediate-Early Proteins
"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Descriptor ID |
D017874
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MeSH Number(s) |
D12.776.460 D12.776.964.925.968
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Concept/Terms |
Immediate-Early Proteins- Immediate-Early Proteins
- Immediate Early Proteins
- Proteins, Immediate-Early
- Proteins, Immediate Early
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Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".
Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".
This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2003 | 5 | 0 | 5 | 2004 | 1 | 1 | 2 | 2006 | 2 | 1 | 3 | 2007 | 1 | 0 | 1 | 2008 | 1 | 1 | 2 | 2010 | 3 | 1 | 4 | 2011 | 0 | 1 | 1 | 2012 | 1 | 1 | 2 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.
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Salka K, Bhuvanendran S, Wilson K, Bozidis P, Mehta M, Rainey K, Sesaki H, Patterson GH, Jaiswal JK, Colberg-Poley AM. Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential for Endoplasmic Reticulum to Outer Mitochondrial Membrane Protein Transport. Sci Rep. 2017 02 02; 7(1):16.
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Williamson CD, Wong DS, Bozidis P, Zhang A, Colberg-Poley AM. Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected Primary Fibroblasts. Curr Protoc Cell Biol. 2015 Sep 01; 68:3.27.1-33.
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Bhuvanendran S, Salka K, Rainey K, Sreetama SC, Williams E, Leeker M, Prasad V, Boyd J, Patterson GH, Jaiswal JK, Colberg-Poley AM. Superresolution imaging of human cytomegalovirus vMIA localization in sub-mitochondrial compartments. Viruses. 2014 Apr 09; 6(4):1612-36.
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Zhang A, Hildreth RL, Colberg-Poley AM. Human cytomegalovirus inhibits apoptosis by proteasome-mediated degradation of Bax at endoplasmic reticulum-mitochondrion contacts. J Virol. 2013 May; 87(10):5657-68.
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Hildreth RL, Bullough MD, Zhang A, Chen HL, Schwartz PH, Panchision DM, Colberg-Poley AM. Viral mitochondria-localized inhibitor of apoptosis (UL37 exon 1 protein) does not protect human neural precursor cells from human cytomegalovirus-induced cell death. J Gen Virol. 2012 Nov; 93(Pt 11):2436-46.
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Prasad A, Lu M, Lukac DM, Zeichner SL. An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis. J Virol. 2012 Apr; 86(8):4404-19.
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Hanley PJ, Shaffer DR, Cruz CR, Ku S, Tzou B, Liu H, Demmler-Harrison G, Heslop HE, Rooney CM, Gottschalk S, Bollard CM. Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein-Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation. Cytotherapy. 2011 Sep; 13(8):976-86.
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Williamson CD, Zhang A, Colberg-Poley AM. The human cytomegalovirus protein UL37 exon 1 associates with internal lipid rafts. J Virol. 2011 Mar; 85(5):2100-11.
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Bollard CM. Isolating cytomegalovirus-specific T cells for adoptive transfer: are we there yet? Cytotherapy. 2010 Nov; 12(7):857-8.
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Bozidis P, Williamson CD, Wong DS, Colberg-Poley AM. Trafficking of UL37 proteins into mitochondrion-associated membranes during permissive human cytomegalovirus infection. J Virol. 2010 Aug; 84(15):7898-903.
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