Virus Latency
"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
Descriptor ID |
D017735
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MeSH Number(s) |
G06.920.900
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Concept/Terms |
Virus Latency- Virus Latency
- Latencies, Virus
- Latency, Virus
- Virus Latencies
- Viral Latency
- Latencies, Viral
- Latency, Viral
- Viral Latencies
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Below are MeSH descriptors whose meaning is more general than "Virus Latency".
Below are MeSH descriptors whose meaning is more specific than "Virus Latency".
This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2004 | 1 | 1 | 2 | 2006 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2008 | 1 | 1 | 2 | 2010 | 1 | 0 | 1 | 2013 | 2 | 0 | 2 | 2015 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Virus Latency" by people in Profiles.
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Sung JA, Sholtis K, Kirchherr J, Kuruc JD, Gay CL, Nordstrom JL, Bollard CM, Archin NM, Margolis DM. Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells. EBioMedicine. 2017 Sep; 23:52-58.
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Bigley AB, Rezvani K, Shah N, Sekine T, Balneger N, Pistillo M, Agha N, Kunz H, O'Connor DP, Bollard CM, Simpson RJ. Latent cytomegalovirus infection enhances anti-tumour cytotoxicity through accumulation of NKG2C+ NK cells in healthy humans. Clin Exp Immunol. 2016 08; 185(2):239-51.
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Khan SZ, Hand N, Zeichner SL. Apoptosis-induced activation of HIV-1 in latently infected cell lines. Retrovirology. 2015 May 16; 12:42.
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Prasad A, Remick J, Zeichner SL. Activation of human herpesvirus replication by apoptosis. J Virol. 2013 Oct; 87(19):10641-50.
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Fernandez G, Zaikos TD, Khan SZ, Jacobi AM, Behlke MA, Zeichner SL. Targeting I?B proteins for HIV latency activation: the role of individual I?B and NF-?B proteins. J Virol. 2013 Apr; 87(7):3966-78.
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Fernandez G, Zeichner SL. Cell line-dependent variability in HIV activation employing DNMT inhibitors. Virol J. 2010 Oct 13; 7:266.
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Cure P, Froud T, Leitão CB, Pileggi A, Tharavanij T, Bernetti K, Baidal DA, Selvaggi G, Ricordi C, Alejandro R. Late Epstein Barr virus reactivation in islet after kidney transplantation. Transplantation. 2008 Nov 15; 86(9):1324-5.
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Bollard CM, Cooper LJ, Heslop HE. Immunotherapy targeting EBV-expressing lymphoproliferative diseases. Best Pract Res Clin Haematol. 2008 Sep; 21(3):405-20.
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Persaud D, Ray SC, Kajdas J, Ahonkhai A, Siberry GK, Ferguson K, Ziemniak C, Quinn TC, Casazza JP, Zeichner S, Gange SJ, Watson DC. Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy. AIDS Res Hum Retroviruses. 2007 Mar; 23(3):381-90.
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Gottschalk S, Bollard CM, Straathof KC, Louis CU, Savoldo B, Dotti G, Brenner MK, Heslop HE, Rooney CM. T cell therapies. Ernst Schering Found Symp Proc. 2006; (4):69-82.
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