 Apoptosis
"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
| Descriptor ID |
D017209
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| MeSH Number(s) |
G04.299.139.160
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| Concept/Terms |
Apoptosis- Apoptosis
- Programmed Cell Death, Type I
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Below are MeSH descriptors whose meaning is more general than "Apoptosis".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis".
This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 4 | 2 | 6 | | 2003 | 2 | 3 | 5 | | 2004 | 3 | 4 | 7 | | 2005 | 4 | 6 | 10 | | 2006 | 3 | 2 | 5 | | 2007 | 2 | 4 | 6 | | 2008 | 1 | 2 | 3 | | 2009 | 3 | 1 | 4 | | 2010 | 2 | 2 | 4 | | 2011 | 2 | 3 | 5 | | 2012 | 2 | 2 | 4 | | 2013 | 4 | 7 | 11 | | 2014 | 0 | 3 | 3 | | 2015 | 3 | 3 | 6 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apoptosis" by people in Profiles.
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Dillinger B, Ahmadi-Erber S, Lau M, Hoelzl MA, Erhart F, Juergens B, Fuchs D, Heitger A, Ladisch S, Dohnal AM. IFN-? and tumor gangliosides: Implications for the tumor microenvironment. Cell Immunol. 2018 03; 325:33-40.
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Ho CY, Ames HM, Tipton A, Vezina G, Liu JS, Scafidi J, Torii M, Rodriguez FJ, du Plessis A, DeBiasi RL. Differential neuronal susceptibility and apoptosis in congenital Zika virus infection. Ann Neurol. 2017 Jul; 82(1):121-127.
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Paget S, Dubuissez M, Dehennaut V, Nassour J, Harmon BT, Spruyt N, Loison I, Abbadie C, Rood BR, Leprince D. HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs). Oncotarget. 2017 Jan 10; 8(2):2916-2935.
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Awasthi A, Ayello J, Van de Ven C, Elmacken M, Sabulski A, Barth MJ, Czuczman MS, Islam H, Klein C, Cairo MS. Obinutuzumab (GA101) compared to rituximab significantly enhances cell death and antibody-dependent cytotoxicity and improves overall survival against CD20(+) rituximab-sensitive/-resistant Burkitt lymphoma (BL) and precursor B-acute lymphoblastic leukaemia (pre-B-ALL): potential targeted therapy in patients with poor risk CD20(+) BL and pre-B-ALL. Br J Haematol. 2015 Dec; 171(5):763-75.
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Chen B, Zaveri PG, Longtine MS, Nelson DM. N-myc downstream-regulated gene 1 (NDRG1) mediates pomegranate juice protection from apoptosis in hypoxic BeWo cells but not in primary human trophoblasts. Placenta. 2015 Aug; 36(8):847-53.
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Khan SZ, Hand N, Zeichner SL. Apoptosis-induced activation of HIV-1 in latently infected cell lines. Retrovirology. 2015 May 16; 12:42.
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Hu Y, Bobb D, He J, Hill DA, Dome JS. The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma. Cancer Biol Ther. 2015; 16(6):949-57.
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Colberg-Poley AM, Patterson GH, Salka K, Bhuvanendran S, Yang D, Jaiswal JK. Superresolution imaging of viral protein trafficking. Med Microbiol Immunol. 2015 Jun; 204(3):449-60.
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Liu R, Liu C, Chen D, Yang WH, Liu X, Liu CG, Dugas CM, Tang F, Zheng P, Liu Y, Wang L. FOXP3 Controls an miR-146/NF-?B Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. Cancer Res. 2015 Apr 15; 75(8):1703-13.
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Wong C, Chen C, Wu Q, Liu Y, Zheng P. A critical role for the regulated wnt-myc pathway in naive T cell survival. J Immunol. 2015 Jan 01; 194(1):158-67.
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