 Persistent Fetal Circulation Syndrome
"Persistent Fetal Circulation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
| Descriptor ID |
D010547
|
| MeSH Number(s) |
C08.381.423.694 C16.614.694
|
| Concept/Terms |
Persistent Fetal Circulation Syndrome- Persistent Fetal Circulation Syndrome
- Pulmonary Hypertension, Familial Persistent, of the Newborn
- ACD-MPV
- ACD MPV
- ACDMPV
- Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins
- Persistent Fetal Circulation
- Circulation, Persistent Fetal
- Familial Persistent Pulmonary Hypertension of the Newborn
- Fetal Circulation, Persistent
- Hypertension, Pulmonary, of Newborn, Persistent
- Misalignment of the Pulmonary Vessels
- Persistent Pulmonary Hypertension of Newborn
- Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins And Other Congenital Anomalies
|
Below are MeSH descriptors whose meaning is more general than "Persistent Fetal Circulation Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Persistent Fetal Circulation Syndrome".
This graph shows the total number of publications written about "Persistent Fetal Circulation Syndrome" by people in this website by year, and whether "Persistent Fetal Circulation Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 4 | 0 | 4 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Persistent Fetal Circulation Syndrome" by people in Profiles.
-
Giaccone A, Zuppa AF, Sood B, Cohen MS, O'Byrne ML, Moorthy G, Mathur A, Kirpalani H. Milrinone Pharmacokinetics and Pharmacodynamics in Neonates with Persistent Pulmonary Hypertension of the Newborn. Am J Perinatol. 2017 07; 34(8):749-758.
-
Steinhorn RH, Fineman J, Kusic-Pajic A, Cornelisse P, Gehin M, Nowbakht P, Pierce CM, Beghetti M. Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial. J Pediatr. 2016 Oct; 177:90-96.e3.
-
van den Anker JN, Allegaert K. Acetaminophen to Prevent Symptomatic Patent Ductus Arteriosus: Another Drug Bites the Dust? J Pediatr. 2016 10; 177:7-9.
-
Steinhorn RH. Advances in Neonatal Pulmonary Hypertension. Neonatology. 2016; 109(4):334-44.
-
Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99.
-
Wedgwood S, Lakshminrusimha S, Schumacker PT, Steinhorn RH. Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15; 309(2):L196-203.
-
Steinhorn RH. Pharmacotherapy for pulmonary hypertension. Pediatr Clin North Am. 2012 Oct; 59(5):1129-46.
-
Perez M, Lakshminrusimha S, Wedgwood S, Czech L, Gugino SF, Russell JA, Farrow KN, Steinhorn RH. Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15; 302(6):L595-603.
-
Wedgwood S, Lakshminrusimha S, Fukai T, Russell JA, Schumacker PT, Steinhorn RH. Hydrogen peroxide regulates extracellular superoxide dismutase activity and expression in neonatal pulmonary hypertension. Antioxid Redox Signal. 2011 Sep 15; 15(6):1497-506.
-
Bishop NB, Stankiewicz P, Steinhorn RH. Alveolar capillary dysplasia. Am J Respir Crit Care Med. 2011 Jul 15; 184(2):172-9.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|