Mitochondria
"Mitochondria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Descriptor ID |
D008928
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MeSH Number(s) |
A11.284.430.214.190.875.564 A11.284.835.626
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Concept/Terms |
Mitochondrial Contraction- Mitochondrial Contraction
- Contraction, Mitochondrial
- Contractions, Mitochondrial
- Mitochondrial Contractions
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Below are MeSH descriptors whose meaning is more general than "Mitochondria".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria".
This graph shows the total number of publications written about "Mitochondria" by people in this website by year, and whether "Mitochondria" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 | 2003 | 0 | 2 | 2 | 2004 | 0 | 2 | 2 | 2005 | 3 | 0 | 3 | 2006 | 2 | 0 | 2 | 2007 | 0 | 1 | 1 | 2008 | 2 | 0 | 2 | 2009 | 1 | 0 | 1 | 2010 | 2 | 0 | 2 | 2011 | 2 | 1 | 3 | 2012 | 3 | 1 | 4 | 2013 | 2 | 1 | 3 | 2014 | 1 | 2 | 3 | 2015 | 2 | 1 | 3 | 2016 | 1 | 0 | 1 | 2017 | 3 | 2 | 5 |
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Below are the most recent publications written about "Mitochondria" by people in Profiles.
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Jao J, Powis KM, Kirmse B, Yu C, Epie F, Nshom E, Abrams EJ, Sperling RS, Leroith D, Geffner ME, Kurland IJ, Côté HCF. Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon. AIDS. 2017 11 28; 31(18):2475-2481.
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Chapman KA, Ostrovsky J, Rao M, Dingley SD, Polyak E, Yudkoff M, Xiao R, Bennett MJ, Falk MJ. Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. J Inherit Metab Dis. 2018 03; 41(2):157-168.
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Horn A, Van der Meulen JH, Defour A, Hogarth M, Sreetama SC, Reed A, Scheffer L, Chandel NS, Jaiswal JK. Mitochondrial redox signaling enables repair of injured skeletal muscle cells. Sci Signal. 2017 Sep 05; 10(495).
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Oprescu SN, Chepa-Lotrea X, Takase R, Golas G, Markello TC, Adams DR, Toro C, Gropman AL, Hou YM, Malicdan MCV, Gahl WA, Tifft CJ, Antonellis A. Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation. Hum Mutat. 2017 10; 38(10):1412-1420.
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Zhu JY, Fu Y, Richman A, Zhao Z, Ray PE, Han Z. A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation. J Am Soc Nephrol. 2017 Sep; 28(9):2607-2617.
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Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, Jaiswal JK. Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy. Cell Death Differ. 2017 02; 24(2):330-342.
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Williamson CD, Wong DS, Bozidis P, Zhang A, Colberg-Poley AM. Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected Primary Fibroblasts. Curr Protoc Cell Biol. 2015 Sep 01; 68:3.27.1-33.
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Wedgwood S, Lakshminrusimha S, Schumacker PT, Steinhorn RH. Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15; 309(2):L196-203.
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Colberg-Poley AM, Patterson GH, Salka K, Bhuvanendran S, Yang D, Jaiswal JK. Superresolution imaging of viral protein trafficking. Med Microbiol Immunol. 2015 Jun; 204(3):449-60.
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Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Wong HR. Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock. Crit Care. 2014 Nov 19; 18(6):623.
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