 Leukoencephalopathy, Progressive Multifocal
"Leukoencephalopathy, Progressive Multifocal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
| Descriptor ID |
D007968
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| MeSH Number(s) |
C02.182.500.300.500 C02.256.721.500 C02.290.575 C02.839.550 C10.228.140.695.750 C10.228.228.210.150.300.500 C10.228.228.245.340.575 C10.314.450
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| Concept/Terms |
Leukoencephalopathy, Progressive Multifocal- Leukoencephalopathy, Progressive Multifocal
- Leukoencephalopathies, Progressive Multifocal
- Multifocal Leukoencephalopathies, Progressive
- Multifocal Leukoencephalopathy, Progressive
- Progressive Multifocal Leukoencephalopathies
- JC Polyomavirus Encephalopathy
- Encephalopathies, JC Polyomavirus
- Encephalopathy, JC Polyomavirus
- Progressive Multifocal Leukoencephalopathy
- Encephalitis, JC Polyomavirus
- JC Polyomavirus Encephalitis
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Below are MeSH descriptors whose meaning is more general than "Leukoencephalopathy, Progressive Multifocal".
- Diseases [C]
- Virus Diseases [C02]
- Central Nervous System Viral Diseases [C02.182]
- Encephalitis [C02.182.500]
- Encephalitis, Viral [C02.182.500.300]
- Leukoencephalopathy, Progressive Multifocal [C02.182.500.300.500]
- DNA Virus Infections [C02.256]
- Polyomavirus Infections [C02.256.721]
- Leukoencephalopathy, Progressive Multifocal [C02.256.721.500]
- Encephalitis, Viral [C02.290]
- Leukoencephalopathy, Progressive Multifocal [C02.290.575]
- Slow Virus Diseases [C02.839]
- Leukoencephalopathy, Progressive Multifocal [C02.839.550]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Leukoencephalopathy, Progressive Multifocal [C10.228.140.695.750]
- Central Nervous System Infections [C10.228.228]
- Central Nervous System Viral Diseases [C10.228.228.210]
- Encephalitis [C10.228.228.210.150]
- Encephalitis, Viral [C10.228.228.210.150.300]
- Leukoencephalopathy, Progressive Multifocal [C10.228.228.210.150.300.500]
- Encephalitis [C10.228.228.245]
- Encephalitis, Viral [C10.228.228.245.340]
- Leukoencephalopathy, Progressive Multifocal [C10.228.228.245.340.575]
- Demyelinating Diseases [C10.314]
- Leukoencephalopathy, Progressive Multifocal [C10.314.450]
Below are MeSH descriptors whose meaning is more specific than "Leukoencephalopathy, Progressive Multifocal".
This graph shows the total number of publications written about "Leukoencephalopathy, Progressive Multifocal" by people in this website by year, and whether "Leukoencephalopathy, Progressive Multifocal" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukoencephalopathy, Progressive Multifocal" by people in Profiles.
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Dallabona C, Abbink TE, Carrozzo R, Torraco A, Legati A, van Berkel CG, Niceta M, Langella T, Verrigni D, Rizza T, Diodato D, Piemonte F, Lamantea E, Fang M, Zhang J, Martinelli D, Bevivino E, Dionisi-Vici C, Vanderver A, Philip SG, Kurian MA, Verma IC, Bijarnia-Mahay S, Jacinto S, Furtado F, Accorsi P, Ardissone A, Moroni I, Ferrero I, Tartaglia M, Goffrini P, Ghezzi D, van der Knaap MS, Bertini E. LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with distinct MRI appearance. Brain. 2016 Mar; 139(Pt 3):782-94.
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Richardson-Burns SM, Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL. Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS. Arch Neurol. 2002 Dec; 59(12):1930-6.
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