Caffeine
"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Descriptor ID |
D002110
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MeSH Number(s) |
D03.132.960.175 D03.438.759.758.824.175
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Concept/Terms |
Vivarin- Vivarin
- GlaxoSmithKline Brand of Caffeine
Dexitac- Dexitac
- Republic Drug Brand of Caffeine
No Doz- No Doz
- Bristol-Myers Squibb Brand of Caffeine
Quick-Pep- Quick-Pep
- Thompson Brand 2 of Caffeine
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Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in this website by year, and whether "Caffeine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1988 | 1 | 0 | 1 | 1989 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caffeine" by people in Profiles.
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Koch G, Datta AN, Jost K, Schulzke SM, van den Anker J, Pfister M. Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates. J Pediatr. 2017 12; 191:50-56.e1.
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Owens JA, Mindell J, Baylor A. Effect of energy drink and caffeinated beverage consumption on sleep, mood, and performance in children and adolescents. Nutr Rev. 2014 Oct; 72 Suppl 1:65-71.
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Ghandour RM, Overpeck MD, Huang ZJ, Kogan MD, Scheidt PC. Headache, stomachache, backache, and morning fatigue among adolescent girls in the United States: associations with behavioral, sociodemographic, and environmental factors. Arch Pediatr Adolesc Med. 2004 Aug; 158(8):797-803.
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Welborn LG, Hannallah RS, Fink R, Ruttimann UE, Hicks JM. High-dose caffeine suppresses postoperative apnea in former preterm infants. Anesthesiology. 1989 Sep; 71(3):347-9.
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Welborn LG, de Soto H, Hannallah RS, Fink R, Ruttimann UE, Boeckx R. The use of caffeine in the control of post-anesthetic apnea in former premature infants. Anesthesiology. 1988 May; 68(5):796-8.
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