Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes.

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Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes.

Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, He Y, Li Y, Ray PE, Gutkind JS. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell. 2003 Jan; 3(1):23-36.

View in: PubMed

subject areas

Animals
Avian leukosis virus
Cell Transformation, Neoplastic
Cells, Cultured
Endothelium, Vascular
Genetic Engineering
Herpesvirus 8, Human
Immunohistochemistry
Mice
Mice, Transgenic
Microscopy, Electron
Neoplasm Proteins
Promoter Regions, Genetic
Proto-Oncogene Proteins
Receptors, Chemokine
Sarcoma, Kaposi
Transduction, Genetic
Viral Proteins

authors with profiles

Ray, Patricio

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Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes.